Description

Pyrantrin Tablet is a highly effective anthelmintic medication containing pyrantel pamoate as the active ingredient. This powerful formulation offers a comprehensive solution for eliminating intestinal worm infections and restoring gastrointestinal health.

Uses

Pyrantrin Tablet is used to treat various types of intestinal worm infestations, including:

  • Enterobius vermicularis (pinworm or threadworm)
  • Ascaris lumbricoides (roundworm)
  • Ancylostoma duodenale (hookworm)
  • Necator americanus (hookworm)
  • Trichostrongylus colubriformis and orientalis

Benefits

  • Effectively expels a wide range of intestinal worms
  • Suitable for treating single or mixed worm infestations
  • Provides relief from symptoms associated with worm infestations
  • Single-dose treatment for most infections
  • Well-tolerated by most patients
  • Does not require fasting or purging
  • Suitable for various age groups with adjusted dosing

How It Works

Pyrantel pamoate, the active ingredient in Pyrantrin, works by causing paralysis and subsequent expulsion of the intestinal worms from the body. It acts on the neuromuscular junction of the worms, leading to their immobilization and eventual elimination through the feces.

Duration of Action

The medication typically begins working within 2-3 hours after administration. Most worms are paralyzed and expelled within 24-72 hours of taking the medication.

Dosage

Age/Weight Recommended Dosage (Tablets) Frequency
6 months – 2 years 1 tablet Single dose (Once)
2 years – 6 years 2 tablets Single dose (Once)
6 years – 12 years 4 tablets Single dose (Once)
12 years and above 5 tablets Single dose (Once)
Other Adults 6 tablets Single dose (Once)

Warnings

Pyrantrin should not be used in patients with known hypersensitivity to pyrantel pamoate or any of its components. Caution should be exercised in patients with liver or kidney impairment, as dosage adjustments may be necessary.

Side Effects

Common side effects of Pyrantrin may include nausea, vomiting, abdominal pain, and diarrhea. These side effects are usually mild and temporary.

Pregnancy and Breastfeeding

Pyrantrin Tablet should be used during pregnancy only if clearly needed. Consult a healthcare provider before using while pregnant or breastfeeding as safety has not been firmly established.

Interactions

  • Piperazine (may antagonize effects)
  • Theophylline (may increase theophylline levels)
  • Chloroquine (potential for decreased absorption)
  • Certain antacids (may reduce effectiveness)
  • Other anthelmintic medications (potential interactions)

Precautions

Take Pyrantrin Tablet exactly as prescribed. No special preparation such as fasting or purging is required before taking this medication. All family members should be treated simultaneously if one member has pinworms. Maintain good hygiene practices including handwashing and changing undergarments and bedding frequently.

Important Information

Pyrantrin Tablet can be taken without regard to food or time of day. Purging is not necessary prior to or during therapy. Complete the full course of treatment as prescribed, even if symptoms improve. Follow-up examination may be necessary to confirm complete elimination of the parasites.

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